It is easy to find NPC and target mobs by auto-path. In your quest list, quest NPC, target mobs and quest notify spot NPC are usually shown in green words. When you move mouse over these green clickable words, the green words will become yellow. Click the words to start auto-path.
Click "Nearby NPC" button beside mini map, and a list will show you the NPCs around you. Click NPC's name to realize auto-path.
Press shortcut "M" to open area map, right click a spot and auto-path there.